>tfw microbiologist
>tfw nobody cares about antimicrobial resistance
>tfw it's right around the corner, not a boogyman like global warming
>tfw it's going to hit humans like a ten ton brick because we're unprepared
/pol/ is probably the only place that will rejoice, so I'm delegated to posting here about it.
Expect most of Africa, India, South America, Russia, and China to be gone by 2050. Europe and North America will probably be OK if they react responsibly instead of letting immigrants fleeing the diseases pour into their countries because they're far, far more sanitary than anywhere else on the globe. Japan and Australia will likely have a very high chance of being completely unharmed.
This is the great filter.
I hope you're prepared.
I'd suggest at least getting basic emergency supplies like dried rations(homemade are much cheaper) and emergency water purifiers.
You are not a microbiologist.
>>59427501
fascist/right-wing elements are being created as grassroots projects that vary from lone individuals (canada, australia) to moderate awareness (america) to full-blown fuck you, liberalism (poland).
these movements are all in reaction to the bullshit PC culture/infectious liberalism of "multicultural" societies.
Westerners are going to become increasingly aware of their societies transforming and so-called "xenophobic" or anti-foreigner sentiments will grow.
repelling sick immigrants will be a walk in the park.
but we aren't medically prepared. I spoke to an infectologist (is that what they're called? The guys who specialize in disease prevention and containment?) at the hospital I used to work at and his thoughts on the matter were "soon, we will all be fucked. A simple cut will begin to be the death of people again".
Can you elaborate ?
Do you mean there's going to be a great epidemic ? Or a systemic crash ? I don't see what you're talking about.
>>59427501
The weird thing is that although microbial resistance to antibiotics has been growing steadily since Penicillin was discovered, the virus has the scoreboard completely locked down for number of people killed.
https://en.wikipedia.org/wiki/1918_flu_pandemic
Discounting endemic infections such as Spanish Flu, regular influenza kills more people each year than all the superbugs combined.
https://en.wikipedia.org/wiki/Human_mortality_from_H5N1
>>59427565
PhD student at University of Pennsylvania in the bacteriology graduate program. My working thesis is currently on Yersinia pestis involvement in resistance to cationic antimicrobial peptides.
>>59428024
Literally second sentence names the devil
>Antimicrobial resistance
In short, we've used hamfisted tactics to combat disease for so long that we're likely to witness basic evolution to fuck us over hard.
>>59427501
Any good books/websites on this issue?
>>59427501
didn't i just see an article about an upcoming ban in the states?
how do you feel about the argument that it's a never ending constant arms race, back and forth between resistance and new antimicrobial methods?
>>59428276
Right I see.
Is there any professor sounding the alarm on this particular problem ? What timeframe are we looking at ? 5-10 years ? more ?
>>59428174
You are not a microbiologist.
>>59428460
I'll have a piece of fancy paper that says I am in about 4 weeks.
How will I know when it is happening?
>>59427501
Shouldn't you be designing a magical bacteriophage instead to posting on 4chan?
>>59428532
You are not a microbiologist.
How can I prepare? How can I avoid being affected?
What is there to fear?
Alright, microbial resistance is going to be a problem in the near future, but, at the same time, the big reason why there's almost no research into new antibiotics is because there's almost no market, at the moment for new antibiotics and they cost just as much as other new medications to develop.
We're also right on the cusp of nanomechanical immunity to disease and microbes, so, there's that as well.
>>59428662
You are a cockroach.
>>59428532
Then you're not
Also
>what are synthetic antibiotics.
Imbecile
>>59427565
>>59428662
>>59428460
Fuck all you niggers. Regardless of his credentials he is correct and is parroting the opinions of many actual microbiologists. Nanomachines may be a solution, but you better believe that the problem will affect people before we decide to solve it.
>>59427501
A microbiologist, after years of schooling, would probably know the difference between delegated and relegated.
I hear there's some promising research being done on alligator immune systems. They are able to heal open wounds while being submerged in swamps teeming with bacteria and almost never develope an infection. Also some bacteria found in an underground cave that has been sealed off for millions of years developed some form of immunity not seen in any other known creature.
We'll just develope the next thing, big pharma jews will make bank, and hopefully this time around we don't hand out antibiotics like they're water to anyone who wants some.
>>59428728
>>Also
>>what are synthetic antibiotics.
almost non-existent?
off the top of my head
quinolones, oxazolidinones, diarylquinolines, and sulfonamide
the free market will fix it
>>59427501
Hope it hits the poor, women, kikes, spics, and niggers a lot harder than it will hit white men.
I'd love for nothing more than for all the fucks in this picture to drop dead.
>>59428850
He is not a microbiologist.
>Haven't touched antibiotics in over a decade
>Know wilderness survival, basic farming, and how to hunt.
>Know how to build
Im ready boss.
>tfw antibiotics are literally the only thing that stops my cystic acne
What do OP-San? I too am worried about these things, but until my bod can mimic these drugs then I have nothing else to turn to.
>>59429262
What you can do is die like the genetic inferiority that you are.
>>59429262
Sorry anon, but you'll be a giant walking zit in less than a decade.
>>59427501
You can blame retarded patients and jew doctors in an equal 50/50 split for this.
>DOCTUH I HAVE A COLD
>You'll get better on your own.
>I NEED ANTIBIOTICS
>But you have a virus and antibiotics don't work on viruses
>GIVE THEM TO ME
>DOCTUH I HAVE A COLD
>Oh heretic jesus pissing on a roman! That's not good at all! You'll need a full regimen of shekelzionistrolene! Apply this chosenonedafil ten times a day wherever you want! It does nothing but I can charge the insurance companies top dollar!
>>59429224
>Haven't touched antibiotics in over a decade
>Am autistic and have trouble tying my shoes
Help, bra.
>>59427501
Sounds good to me. Is this supposed to be bad?
>>59429323
>>59429332
Wew lads.
>>59427501
just stay topped up on C8 MCT's ..I have been taking several grams a day of lauricidin for a long time now and never get sick..
C8 MCT are even more potent..
>>59427501
>Europe and North America will probably be OK if they react responsibly instead of letting immigrants fleeing the diseases pour into their countries because they're far, far more sanitary than anywhere else on the globe
so we're fucked then.
>>59429224
I'm not a PhD in microbiology but I think the risk we're talking about is that we'll have bacteria that are resistant to any kind of antibiotics, so that when you'll truly need them, they'll be completely inefficient.
So I think you having used or not antibiotics will have little impact.
Resistant gonorrhea is already becoming a thing.
Aids 2.0 is in the making.
Personally i fear for anything that affects the lungs, becomes airborne and resistant.
is op a idiot. america is ground zero for drug resistant strains and anti biotic resistant strains
its where we find "super" aids popping up first and being most common. its the home of drug resistant tb
its because we over medicate people. even non disease related medications affect the likely hood of drug resistant strains popping up
we pump antibiotics into cattle for fuck sake. not the cleanest of creatures and ones we eat. great in the short term but after decades it can cause problems
>>59429379
Maybe if you agree to be my buttslave and work the fertilizer into the fields by hand.
>>59428024
We are using so many anti-biotics that bacteria is becoming immune.
You can take a guess where that might go wrong.
>>59429519
Wouldn't someone who abuses antibiotics have a less robust autoimmune system ?
>>59427501
Mycologist here.
I feel your pain. We have the biotechs having us living in the fucking woods collecting new varieties err day. How many samples of Turkey Tails do you fucking need.
ironically, it is hospitals where these super-bugs live.
In the wild, the super-bugs mix with non super-bugs, so they lose their ability to resist antibiotics.
>>59427501
As a medical student I have much respect for you and hope to understand even a fraction of that knowledge you do. But could I ask you a favor?
>>59429639
idk to be honest.
>>59429519
We already do have strains appearing that are resistant to all known antibiotics. They just haven't spread outside of very small areas yet.
>>59427501
>instead of letting immigrants fleeing the diseases pour into their countries because they're far, far more sanitary than anywhere else on the globe.
If the current crisis is any indication, that's exactly what's going to happen.
We're going to drown in a sea of niggers.
>>59429519
You are correct sir.
>>59428460
Youre a faggot.
>>59428870
what if he meant delegated, but delegated by whom?
>>59429741
Bacteria do not reproduce sexually you dumb faggot
>>59428727
You are not a microbiologist.
All you fags are wrong.
Genetic modification will simply solve this in a few years. They already discovered a cheap and simple way to alter DNA called CRISPR/Cas9. They could simply cut out the resistant bacteria's allele that prevents being destroyed by antibiotics.
/pol/ fags BTFO
>>59428728
Rare and all centered around one functional group.
>>59428708
>How can I prepare?
avoid antimicrobial soaps that "kill 99.9999% of bacteria" unless absolutely necessary. Finish any antibiotic regimen you're prescribed and don't stop taking it before it's finished when you feel better
>How can I avoid being affected?
you can't. That's the scary part.
>What is there to fear?
superinfections, aka diseases evolving to the point where few to none of our drugs are effective. At that point, either you're totally susceptible to the disease and medicine won't treat it or we'll have to resort to the heavy duty antibiotics, the ones with heavy side effects.
>>59428662
You're a sandfaggot.
>>59429976
yeah? and how do those bacteria become more numerous than the anti microbe resistant ones?
death has a funny way of not allowing reproduction
>>59429262
When the ashes of civilization are rested, and the few scramble from the ruins you can emerge into glory as Spott, the great leader of the Zitzons
Guys, I hope you're not actually taking OP seriously.
Is antibiotic resistance a real threat? Yes.
Will antibiotic resistance wipe out entire countries? No.
Worst case scenario, life will return to the way it did before we had antibiotics. Even then, medical technology has improved a lot since then, so things will still be better than they were 100 years ago. The only serious threats will be plagues, but we'll be able to create a vaccine for them before they wipe out too many people.
>>59429601
It's actually not because of how much we medicate people, a larger proportion of the problem is the fact that we pump our livestock full of antibiotics and then it ends up in the environment where application isn't controlled whatsoever. The big reason Europe isn't seeing so many antibiotics resistant strains of common bacteria is because they're not allowed by law to pump their livestock with antibiotics.
>>59428850
We didn't say anything about his argument.
We are simply saying that he is not a microbiologist.
>>59427501
God I hope it goes down like that. Based quarantine. Removal of all shitskins. But it will happen to the west first imo because I assume we use antibiotics more.
http://www.telegraph.co.uk/news/science/science-news/11331174/First-new-antibiotic-in-30-years-discovered-in-major-breakthrough.html
http://www.technologyreview.com/news/423539/new-type-of-drug-kills-antibiotic-resistant-bacteria/
http://www.theguardian.com/science/2015/jan/07/antibiotic-drug-resistance-teixobactin
Here is the truth. While new drugs will be available. It will be treated like Vancomycin and Methicillin. Prohibitlity expensive, especially for the developing world. The factory Farm industry will be majority effected as well.
>60% of the third world will die not because they have to but because profits.
>MFW the Merchant interests works in our favor for once
>>59430246
Shitskins have better natural defenses to common bacteria than us sheltered white people. You moron.
>>59429601
Also the antibiotic residue in cattle is what makes fat Americans a different kind of fat than for example Europeans.
>>59430278
>implying this wasnt planned
>Why contain it?
>S'cool.
>>59430131
It's called sitting down on the toilet, taking a big shit, then, after you're done shitting, getting up, giving yourself a boner, and then dipping your cock into the poop in the toilet. You can even just scoop out the poop with your hand, squeeze your cock so the urethra is widened and put some shit in the urethra.
>>59429930
bacteria do have 'sex' and exchange DNA with each other.
>>59429639
eh, its a pretty complex issue. I'd explain but I'm too lazy
>>59430425
It's called recombination., fucking moron.
>>59429995
I'm a bit confused.
You're saying that we are using antibiotics excessively, leading to that %.01 microbe becoming a killer.
So why would you avoid taking antibiotics - in the form of cleaners, soap, etc - if you're going to be fucked by the %.01 that resists it anyway?
>>59430306
I think that only applies to local bacteria?
What the fuck?
http://www.chron.com/news/houston-texas/article/Reward-offered-in-Medical-Center-hit-and-run-1977917.php
>>59430493
The point of antibiotic regimes is not to totally wipe out the present bacteria, but to reduce their numbers low enough to allow the body to fight them off.
This way, even with 0.01% of bacteria being resistant, there's still enough normal bacteria around to drive them out through natural competition.
However, buttblasting the body with antibiotics kills all non-resistant bacteria, leaving behind only the resistant bacteria which can then multiply because of the lack of any competition.
I hate to say this but humanity needs this. It's the only way to restore balance.
>>59430493
We as a society use antimicrobial soaps, etc way more than we should-it's overkill. If we settle for less intensive soap that still kills the bad guys that are going to cause major problems, we limit the exposure of bacteria to the heavy duty antimicrobial action. The less bacteria is exposed to antimicrobials, the less likely they'll be to become resistant to it on an individual basis and the longer it will take them to become resistant to it in the long run.
Using antimicrobial soap less=that soap stays useful longer
>>59430583
Not really, because what they're actually better at withstanding is the body's on natural defenses to bacteria, things like excessive periods of time with a fever, ability to survive parasites living inside of their systems, etc.
All the white people defenses to things like this have been falling off since we discovered how that separating our waste from our drinking water decreases infant mortality.
Basically, we're the descendants of people who would otherwise be dead had we not cleaned up our food and water sources. Shitskins are the people, who, generally, are the ancestors of people who survived similar or worse circumstances.
A valid example would be Mexicans versus Americans drinking water in Mexico. It's not "good for them" it's just not, almost, fatal either.
Bacteriaphages are the answer
>Using alcoholic hand sanitizers
ISHYGDDT
>>59427501
>if they react responsibly instead of letting immigrants fleeing the diseases pour into their countries
Welp, we're fucked
>>59427501
http://www.independent.co.uk/news/uk/gonorrhea-could-become-untreatable-due-to-antibiotic-resistance-a6787136.html
>super gonorrhea
The degenerates will get fucked LOL
>>59429359
The biggest contributor to antibacterial resistance is using the drugs on farm animals.
>>59430871
Again, this is defense against only local bacteria. It doesn't matter that your shitskin ancestors drank poop water for generations. If a new bacteria arises that shitskins have never encountered before, it will likely kill them just like it would white people.
Is this some indian under proxy?
>>59427501
wow i came in this thread thinking you were going to give some crazy happening theory
but you just got butt blasted and left
swaying my cranium
to be sincere
kinfolk
>>59428708
>how can I avoid being affected
pray daddy fucked the right woman and your immune system can handle it
>>59429976
>cut out the resistant bacteria's allele
Oh my gosh, you've found a total end run around evolutionary adaptation! It's a good thing there's not trillions of the little buggers with ultrashort generation times which will eventually select for a mechanism to defeat your cunning plan.
>>59427501
Australia could have survived, but they started #illdiewithyou instead
Argentina is almost sanitary as Europe man , the only problem they have is ghettos full of niggers , a problem of which europe can easily relate to aswell.
I think , althought im not sure , Uruguay faces a similar situation, but the rest of SA is a shithole.
>>59427501
>Japan and Australia will likely have a very high chance of being completely unharmed.
>TFW YOU REALIZE INDIA HAS BEEN EATING POO FOR CENTURIES IN PREPARATION FOR THIS
My mom is a microbiologist too. She doesn't care about superbugs, which makes me not care.
How can I go against me old mum?
>>59431018
>mfw 60% of blacks in America have gonorrhea
http://www.cdc.gov/std/stats12/minorities.htm
>>59427501
Nothing will happen. Humans have literally never been even remotely close to extinction before the advent of antibiotics.
>>59430732
I was laying in bed listening to a talk radio show .. the topic was the observation of what some were considering the statistically significant death rate of Microbiologists from causes not related to their field of work.
All of a sudden that name was read and it hit me like lightning.. he was my childhood friend. A neighbor a few years older than me .. He graduated from Worcester Polytech in Massachusetts .
It was a topic rife with speculation as to why so many people in that field were showing up dead from un-ordinary causes..
>>59429976
>Genetic modification will simply solve this in a few years. They already discovered a cheap and simple way to alter DNA called CRISPR/Cas9. They could simply cut out the resistant bacteria's allele that prevents being destroyed by antibiotics.
You are literally retarded
>>59431130
Aint no bacteria ever developed a resistance to bleach. Some things they're just fucked for.
Viruses though, we may never be able to outsmart.
So... I guess investing in nanotechnology will be profitable then? Anything else?
>>59429607
Wow. Not only did you not understand that he's saying you're stupid because it doesn't matter whether you've touched antibiotics as they'll be worthless, BUT
you went as far as thinking he's as dumb as you are. Nice one.
>>59427501
MY PLANS MUST BE ACCELERATED
>>59427501
I don't see Russia going anywhere. They have a massive amount of empty land and low population density. I'll confess that I don't know the effects of cold temperatures on microbes, but I imagine the sub-Arctic climate would help slow the spread of any sicknesses.
Also my dad works for Nintendo. I have a 4DS but I can't show you or he'll lose his job.
>>59430405
> a literal definition of shitposting?
>>59427501
Nothing will happen. Humans have literally never been even remotely close to extinction before the advent of antibiotics.
Jewish janitors will delete my reasonable post because it doesn't fit the fearmongering narrative.
>>59430461
It's bacteria sex
>>59431304
FUCK YOU
>>59427501
Nice. Ethnic cleansing.
>>59431532
cold exposure has been shown to increase white blood cell count increasing imune response.. I religiously practice cold exposure.. cold showers daily, swimming in cold ocean water, sitting around nake at home with no heat on.. I only got sick during the New England Winter of 2011-12 in thepast twenty years.
I attribute that to the Fukushima Nuclear pollution which traveled the globe weakening my immune system..
>>59430461
>It's called recombination., fucking moron.
Actually it's called bacterial conjugation.
>>59430278
> notice doctors are charging prohibitively high prices for antibiotics
> thisisanoutrage.jpg
> use the government to force doctors to lower prices at gunpoint
> everybody now gets and uses antibiotics on everything, even the farm animals
> excessive usage results in bacteria developing antibiotic resistance
> notmyfault.jpg
> itwasdajoos.jpg
>>59427501
We just have to replace all domestic and hospital aluminium surfaces with copper or brass. And reintroduce drugs from the 70's. We'll be fine, chill.
>>59427501
pls b reel
pls be reel
pls be reeal
>>59427501
>Having a cordillera so big and cold only Uruguayan rugby players can survive it eating each other
>also the dryer desert in the world, where not even bacteria can live
>several thousand of kilometres of Pacific ocean keeps us away from Asia and Oceania
>in the far south we have the Fucking Antarctica as a barrier
I'm ready bitch
Pic related
>>59431083
Not really, because the fever isn't caused by the bacteria, it's your fucking body's reaction to invasion. There's other factors as well.
For example, if you take the population of a given area, and then spread them out evenly, the closer each individual is to one another, the greater their chance of passing on a disease. This is why the plague devastated Europe and did Dick all to Africa.
Also, diseases that come from Cities are naturally more complex than those that arise in the countryside. Europe should be pissed at us for breeding superbugs that will do nothing to us because of how far away from one another we live, but would devastate most of Europe because of how close everyone lives to one another.
>>59431677
Finally get to kill all those Chinese you failed to exterminate 70 years ago without lifting a finger.
Right?
Im with you OP. I remember seeing something in the news a couple months back about "the end of antibiotics", but no one is talking about it. Why is it so unlikely that new antibiotics can be created?
Also Im travelling in Central America and yeah, hygeine here is non existent. I got travellers diarrhea and bought some anti diarrheal at a gas station. Active ingredient is Firazolidone. After reading up on it I decided to just toss it in the trash. Says it was banned in the States 25 years ago and is a known carcinogen.
>>59430791
>However, buttblasting the body with antibiotics kills all non-resistant bacteria, leaving behind only the resistant bacteria which can then multiply because of the lack of any competition.
Like when you take antibiotics and all of a sudden c.difficile starts buttfucking you out of nowhere
>>59428989
You do know that white men can be poor too ...ugh nevermind you're an idiot.
>>59431368
Are you retarded?
60% of cases are black, not 60% of blacks
>>59431945
take S. Boulardii for that..
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805518/
>>59427501
>>59427565
>>59428174
OK OP, I'm illiterate on micro-biology.
Wouldn't a fever kill them? What does the Human Immune system do to Bacteria?
https://www.youtube.com/watch?v=EQ9bP6wo8rA
Very much related. China will never be a world super power.
>>59432087
the problem is, when white people get a fever, they die, because white people's ancestors for the last 100 years or so, at least 70 years, haven't had to endure a good strong bacteria killing fever...
>failed pharm students trying to be relevant
Is there anything more pathetic?
>>59429359
Please stop spouting this utterly retarded faggotry. It's the farming industry that is really killing us.
>still just a student
>im so knedlgeable hheheheh
literally kill yourself
>>59427501
Wasn't there news a few day back that some brits found traces of resistence to the antibiotica of last resort or something?
>>59430791
>However, buttblasting the body with antibiotics kills all non-resistant bacteria, leaving behind only the resistant bacteria which can then multiply because of the lack of any competition.
I remember reading a story on /pol/ about the Chinese getting massive amounts of antibiotics and prescribing them for everything. Anyone know any details?
>>59429601
Disagree. India is more likely of ground zero. IIRC, they don't need a prescription for antibiotics, have denser populations, and have a good vector to distribute the MDR bacteria (ie can't poo in loo).
>>59428429
A lot of people have been talking about it for years but because of a number of problems (doctors overprescribing to avoid malpractice, corrupt big pharma pushing drugs people don't need, ect.) noones done anything. Essentially we're going to get to the point where antibiotics essentially don't work anymore (or at least none but the really heavy duty stuff and even that will be less effective). Medicine for fighting infection is going to regress to where it was in the 1920s.
>>59432411
I really hope China gets obliterated
>>59427501
Maybe if we didn't breed and slaughter 60 billion animals per year and pump them full of antibiotics
>>59427501
>Expect most of Africa, India, South America, Russia, and China to be gone by 2050.
Sounds like a pretty goddamn good deal.
>>59432411
>>59432510
oh shit it was just posted
>>59432166
>>59428174
Does this have anything to do with R-plasmid evolution?
>>59427501
I look forward to the return of dark ages medicine and people dying by 30. We be black now bitches
>>59430158
>Will antibiotic resistance wipe out entire countries? No.
Chances are likely, no it isn't.
Is it a real possibility, yes it is.
All it takes is one cheeky fucker to become immune to mostly all treatments, have a high infection and kill rate, and get airborne in one shit country.
>>59432859
>All it takes is one cheeky fucker to become immune to mostly all treatments, have a high infection and kill rate, and get airborne in one shit country.
It's much more likely to get spread to many people via crop contamination from the feces/manure the bacteria grows/mutates in. It's not antibiotics consumed by humans that are the primary concern. It's the antibiotics we give to livestock that is the problem. There are only 7 billion humans, whereas there are 60 billion livestock killed per year. All of them shit, and many of them are force fed antibiotics.
>>59431925
Ok great, you can be resistant to fucking fevers, the most minor symptom of any disease.
Tuberculosis and diarrhea will still destroy large swathes of Indians (protip: It already is), so I think being resistant to fever is pretty much moot.
>>59432803
What?
Mortality rates were skewed in the "dark" ages by infant mortality. Most people lived until 60 or so.
>>59429629
Merkel will import more refugees to pay for the bacteria's pensions?
>>59427501
>Expect most of Africa, India, South America, Russia, and China to be gone by 2050.
>tfw microbiologist
>Japan and Australia will likely have a very high chance of being completely unharmed.
This is the best news I've heard in years.
I'm confused, is OP really a microbiologist or not ?
also superbacteria is not exactly something new, everyday there is cases of people having MRSA (especially people who practice any form of grappling) or some kind of fucked-up pneumonia acquired in hospital bed.
Microbiology/Epidemology grad student here and I will take time off from writing my thesis to give you something to think about.
>Antibiotic Resistance (AR) genes take energy to express
>If not under pressure from antibiotics then it is detrimental for bacteria to have them, so they get out-competed.
>Bacteria are not driven to stack DNA, they are driven to minimize, therefore it's highly unlikely for a superbacteria to form
>Hospitals breeding ground for antibiotic resistance because all microbes in the building are exposed to antibiotics at some point.
>The problem is not a superbug wiping out the world
>The problem is you can not do surgery safely anymore
>Avoid going to hospitals for unnecessary shit
>>59434526
He's a necromancer apprentice
>>59432087
Most bacteria don't harm us at all. They can come in, hang out and move on no problem.
Some bacteria make us sick, and our bodies react with fever to reduce their reproduction rate, ruuny nose and diarrhea to expel the pathogen, and headacje and discomfort so we sit in bed and let our bodies rest. In the meantime our white blood cells try to figure out how to attack the pathogen. Sometimes it works, sometimes it doesn't.
Some pathogens are so devestating that without drugs we would most likely die from them. Our bodies are just no match.
There are probably millions of types bacteria in the world (just like OP, I am not a microbiologist), but only a few dozen are responsible for our most serious and common diseases.
>>59431925
how likely is this op?
>>59427501
>>tfw it's right around the corner, not a boogyman like global warming
Because it's the real happening that they really want because it will finally thin the herd without people being able to directly point fingers at anyone.
>>59429629
So... this means homos will be Btfo by super aids?
>>59434917
It's not planned, we just fuck up all the time. You'd be surprised at how little we know about gene drives
>>59434873
Can he at least conjure a dead cat ?
>>59427501
How can I prepare myself, tell me /pol/? What do I need to buy? What protocols should I make to survive it?
>>59434870
>>Avoid going to hospitals for unnecessary shit
Look everyone, he doesn't want basic healthcare for everyone. He's a fucking conservashit trying to once again save just the tiniest bit of cost, even if it means saying good bye to grandma a little bit early.
What if the migrant crisis is in anticipation of something like this where the majority of the populations in places such as various African countries will be wiped out so importing a couple million of them is for genetic diversity down the line?
>>59428174
I could find out your name with that info
>>59435316
It's to replace whites once it all goes down, as the first world immune system has been cradled to worthlessness.
>>59434870
>The problem is you can not do surgery safely anymore
>i have a very likely chance of having to get heart related surgery in 30 years so
>>59427501
>Guys it's 2020 we have to let those sick immigrants into our country I mean COME ON!.
>>59435207
Fucking wash your hands you filthy animal
>>59428870
Many scientists have poor mastery of written language
>>59428276
It's a good thing evolution was just made up by satanists trying to steer people away from the wor dof our Lord.
>>59435425
gotta fuckin edgelord over here
>>59431940
>Why is it so unlikely that new antibiotics can be created?
Two mains reasons, one is profit, and the other is biological.
Profit wise, it costs billions of dollars to bring any new drug to market, due to regulations. It also takes a long time too.
Lets say you spend a year and 5 billion dollars making a new antibiotic. You enter a market tht is already saturated with other antibiotics, and in about 10 or 20 years your product is defunct because bacteria have developed an immunity to it. For big pharmaceutical companies there's just more money if developing niche drugs for diseases that affect rich people.
Now for the biological side of things. Antibiotics are just bacteria that weaken or kill other bacteria. There are many ways single celled organisms like viruses and bacteria like to prey on each other, and unfortunately we are running out of them.
When antibiotics became widespread they were so great that people started looking for as many of them as they could find, and we found them. We found almost all of the ones that we can easily find.
We're currently looking for new places to look for antibiotics.
http://phys.org/news/2015-11-students-soil-antibiotics.html
Hopefully there are actually more antibiotics out there, otherwise we'll have to start making them ourselves...
Which is where >>59429976
ight actually not be quite so retarded. If you think it would be easy to design a custom antibiotic though you couldn't be more wrong. Even with a tool as cheap and easy as CRISPR to help, it isn't at all simple.
>>59429945
OP confirmed not a microbiologist, into the trash it goes.
>>59435566
Nice try, too much anti-bacterial soap will only accelerate it.
>>59429593
>Antibiotic resistant AIDS
Netherlands please just read wikipedia or something
>>59435796
>Antibiotics are just bacteria that weaken or kill other bacteria
Please shut the fuck up, you do not know what you are talking about.
Most antibiotics that are frequently used these days are structural analogs of the very first antibiotic, penicillin.
The goal of these types of antibiotics is to inhibit the cross-linking of peptidoglycan in bacterial cell walls, causing the bacteria to lose it cell wall and suffer from the pH of the environment, or other factors.
Methicillin and other major antibiotics differ by a few chemical structures. The problem is, bacteria develop, by chance, ways to process these antibiotics so that they are no longer incorporated into peptidoglycan.
I have no idea where you got this non-sense about using bacteria as antibiotics. I think what you meant to say was that we find many antibiotics by discovering bacteria that produce them. We don't actually use the bacteria to fight other bacteria, but instead use the bacteria to mass produce antibiotics which are then placed in pills, etc.
Even then, we can often create new antibiotics on our own in the laboratory, but thats pretty difficult.
>>59427772
>>59427501
I've had numerous cuts and grazes, some quite bad, and never required antibiotics. It seems quite rare that this happens.
>>59435699
It's true though, that doesn't make him an edgelord. It's the world we live in now that it's that easy to identify and track people down.
>>59428969
Underrated post
>>59428711
You think anyone besides the wealthy will have access to nano tech?
>>59435013
Fuck dammit
Aids is a Fucking VIRUS, not a bacteria
If it were a bacteria will be so much easy to cure
>>59431603
>he hasn't heard of the Toba supervolcano eruption
>>59428711
>We're also right on the cusp of nanomechanical immunity to disease and microbes, so, there's that as well.
There's no way we are, sorry.
>>59436760
most of the antiobiotics that are part of the problem are given to livestock. Not humans. We get contaminated from their feces which we use to grow crops.
China is gonna fuck us all over because they won't stop feeding antibiotics to pigs
>>59437528
Surely the crops get thoroughly cleaned by the time they make it to the dinner table?
>>59436331
Perhaps he is thinking of Bacteriophages
My friend said they'll just create new antibiotics out of new things because that's how science works by inventing new shit.
>>59428174
Biophysics undergrad that works in an antimicrobial peptide lab. The peptides we work with destroy bacterial membranes and therefor it is unlikely bacteria will evolve a resistance to them. What peptides do you work with?
>>59438353
Mind = blown
JUST INVENT NEW THINGS, WAKE UP SHEEPLE
>>59438353
It's so simple!
>>59427501
>>tfw nobody cares about antimicrobial resistance
>>tfw it's right around the corner, not a boogyman like global warming
WHERE IS THE PROOF CHICKEN?
>>59438405
But surely you can't treat people with those, since our bodies are highly dependent on many other forms of bacteria. Treating them with drugs that destroy bacterial membranes will just make them very ill or kill them (the person being treated).
>>59427501
sounds too good to be true
>>59437675
Bacteria is difficult to completely wash off. Especially for certain types of vegetables. Most people don't seen to wash their produce at all. It only takes one person to get contaminated to start an outbreak.
>>59427501
Indeed biological attacks are a scary proposition; as is anything related to the energy system. That blackout in 2002 or whenever it was was a fucking nightmare and it only lasted a couple days. Imagine no power for a week or more. One or both will happen before long, I imagine.
>>59427501
Lives in rural Usa, feeling comfy
>>59439228
Doesn't sound different from cancer treatment
A good culling would be nice. Maybe if we have to worry about day to day survival we might be less crazy as a species.
It'd really suck if me and my family died, of course.
>>59435566
>American
>Reading the entire thread
Not like I would expect, but goddamn
lol
a) taking microbio undergrad courses doesn't make you a microbiologist
b) researchers create scary boogeymen to grab funding for their little niche field of study. your prof fed it to your class and you fell for it.
c) they've been talking about this since the 70s. you're dumb
>>59439449
Doesn't make it medically practical. There's an extremely high chance of killing someone if you destroy all bacteria in their body.
>>59439405
lol, it wasn't that bad. It also stopped a few miles from my house and was fun to watch on the news.
I like to think it was all part of a huge heist.
>>59439635
chemotherapy has a high chance of killing someone too.
>>59439160
Doctors and scientists have been telling us this for at least a decade.
It's real and its coming. Why the fuck is /pol/ so retarded when it comes to some of the most basic things, and completely logical and informed on very obscure things?
>>59439762
And so it doesn't change anything. You still end up with otherwise completely treatable illnesses being deadly.
>>59427501
>I'm a microbiologist here to warn you about the dangers of anti-bacterials
>Expect the places that don't have them to fall victim to this threat
When the anti-microbial holocaust hits? Africa and India are going to win.
The rest of us will be dead, and the third-world will inherit the Earth.
>>59439762
I suppose so. But a purge of all bacteria in a person has an even higher - essentially certain - chance of killing someone.
From what I remember from A level biology.
>>59439635
You act like the antibiotics we use now don't destroy our bacterial flora.
Its all about correct dose. See >>59430791
>>59439762
People use antibiotics in chemo, and any invasive operation, also.
It's all good, boys. Just get yourself hella sick over the next few years so that when SHTF you'll be prepared.
>>59439160
MRSA and Resistant Tuberculosis Strains are bot very relevant examples
>>59439930
Oh I see. I understand my mistake - I'd subconsciously assumed current antibiotics are tailored so as not to affect friendly bacteria. I suppose this is not the case?
So with that in mind, I actually don't see the problem with the peptide based membrane destroyer (someone come up with a better name please). As with antibiotics, I guess it would be a matter of getting the dosage right in order to kill most but not all bacteria?
Apologies for my ignorance, I'm an army officer not a doctor.
>>59439762
there are plenty of chemicals that can easily kill cancer cell. The hard part is finding one and the dosage that don't kill a person after a complete treatment
Antimicrobial resistance is not a huge problem. Anyone with basic genetics training knows why.
Yes, a few more people will die in hospitals. No, it won't be that significant. I'm surprised you microbiologists are so retarded.
>>59439228
It's definitedly an issue that has to be taken into consideration. Treating people with probiotics along with antimicrobial peptides could mitigate the effect of killing off the good bacteria. There are also differences in the lipid composition of the membranes of harmful and beneficial bacteria, so selecting and developing peptides that don't kill off beneficial bacteria while killing harmful one's is another goal of AMP research.
>>59437036
>You think anyone besides the wealthy will have access to televisions/the internet/antibiotics/etc?
>>59440240
>We can just engineer something that will defeat it!
Cancer exists.
Your argument is invalid.
>>59440243
My questions are satisfactorily answered. Good to know there's hope and it's not the apocalypse the media seems to hint it will be.
>>59432219
OP is a week away from getting xir PhD you dumb fuck.
I have never used anti biotics ever.
>giving me false hope of a natural solution for a brighter, whiter future
Why do you do this to me, anon?
That's how you tell apart a serious hospital from the rest. The hospital I go to won't give you antibiotics unless you're pretty much fucked; they know it's extremely dangerous in the long run to whack every little thing with drugs.
Honestly it's frustrating, but when I'm 70 and my system is more robust than other peoples' I'll be glad.
>>59440224
Literally where the word chemotherapy comes from. Use lethal chemicals in barely non-lethal doses to kill the cancer, hopefully before too many non-cancer cells die. We use radioisotopes now, because it's easier to control where they deliver their lethal payload, but the name remains.
>>59440590
That explains my gonorrhoea.
From the ass-fucking.
Get it?
>>59440499
We will be fine; the third world not so much
>>59440703
No, I just don't get it. Like why do people get sick all the time? What are they doing? If I ever got sick I just ride it out, but it is very rare.
>>59440706
>Anti-microbial strains evolve
>The people most-dependent on anti-microbials will survive, and the people least-dependent on them won't!
Sorry, but that is wrong.
>>59440781
Well I was kidding. You're in Canada. You don't get sick because you're around a buncha healthy people who get regularly doused with anti-microbials to keep them that way, so there's nothing for anyone to transmit to you.
>>59440859
I guess that is it.
>>59429262
Why you so poor England?
>Accutaine.
>Retin-A
Literally one year of therapy for an acne free lifetime.
>>59428174
post published papers or gtfo
Using low doses of antibiotics on farm animals is not clever.
>>59440787
But when the strains do evolve we will have the most access to treatments against them whether it is anti microbial peptides, synthetic antibacterials, or whatever else gets invented. The third world won't have the same access unless we give it to them, which will only happen after we save ourselves at which point many of them will die
>>59440903
It is. It's like how soccer moms think vaccines are a government conspiracy because no one gets polio, any more. And the proof is that their kid, who didn't get the vaccine, also didn't get polio.
Diseases aren't magic. They don't immaculately generate and spread based on the ideals you do or don't hold inherent. You can curse god all you want and still get AIDS if you have sex with someone who's got it, when there's a cut on your dick. But there not being a cut on your dick doesn't mean that god spared you from AIDS.
>>59441285
Targetted genetic therapies are iffy as all fuck. They just don't work. When the anti-microbial diseases hit? The survivors are going to bread-out the folks who wore gas-masks. They are going to win on numbers. White people stand a 0% chance of beating black people out of the human-extinction event that is coming.
>>59440199
yeah, antibiotics have no preference. They destroy anything depending on peptidoglycan for protection.
It's funny because in first world countries we don't really consider bacteriological illnesses to be a big deal anymore.
Nobody says "Oh man, he got tuberculosis" or "He nearly died from strept". Of course people know of these things but we don't consider them to be widespread or common. Instead, all we ever think about is viruses. The spooky too-tiny-to-see boogeyman that is going to be weaponized by the bad guys to take out the world.
What people don't understand is that with the rise of more antibiotic resistant bacteria, the more that you'll see once treatable illnesses become a death sentence. Tuberculosis, Staph, E. coli, Tetanus, Salmonella, etc. Any bacteria that can cause a major illness is susceptible for gaining resistance to our current line of defense.
Once this happens, bacteria will become much more dangerous than viruses. Bacteria are absolutely everywhere and grow rapidly. They're in your food, your water, your air. They grow throughout your body.
Bacterial resistance, once widespread, will be catastrophic to all nations.
>>59440499
The solutions you read were still expensive and not at all applicable to third world nations.
Maybe the average American or Brit MIGHT get that treatment initially, but not far into a disease outbreak.
>giving chemo to everyone with a cold
Just be happy you live in a developed nation
>>59429359
Take 2 of these & go for a lie down Mr Burger.
https://www.youtube.com/watch?v=gqCo0s6XKMM
>>59427501
>Australia will likely have a very high chance of being completely
whos irrelevant now motherfuckers
I wouldn't be super worried as of yet. They have antibiotics that are extremely effective at the cost of your well being (better to live a decade or two less then being dead now.) but after those run out.
Yep, its GfuckingG. So many people are going to die within the next fifty years.
sounds like 3rd worlders are gonna get fucked.
Europe will get rekt
America will probably be fine
>>59427501
>this is the great filter
You're a fucking retard.
I'm in the same field as you, there are potential solutions (ever read a single peer reviewed paper in 'our' field in the last couple years?) to this issue, it isn't a massive unavoidable trainwreck. Regardless, even in a worst case scenario, first world medical facilities can do a lot to increase the chances of survival from a terrible bacterial disease like tb. Anyway, kill yourself.
>>59428662
>>59428532
>>59428460
>>59428174
>>59427501
>PhD student at University of Pennsylvania in the bacteriology graduate program
>microbiologist
pick one
Microbiologists are trained physicians who studied for 6 years medical school + 4-6 years training for their speciality.
You are just a biologist I would say. PhD can be completed within 1-2 years, biology degree takes 2-3 years.
On topic, bacterial resistance is only dangerous to people with weak immune systems. This shows how uneducated you are in regards to human health, something a doctor wouldn't do.
I work at a local hospital. We've had three people come in from a local nursing home with sepsis. All three resistant to all antibiotics except clindamycin with only moderate sensitivity it to it. Mind you, these are just regular sick nursing home people with pneumonia. Just wait until the real fucking bacteria that kill people fast start showing up with this type of resistance.
We are currently cohorting (a nice word for isolating in a quarantine) all patients who test positive for klebsiella pneumoniae from thw nursing home on one if our ICUs. See if they make it. Oh, fun facts, clindamycin causes kidney failure after a few days' use. So either these patients get better soon or they are dead.
>>59441820
3rd worlders are going to win. They breed it out. They don't win on ingenuity, or hard work. They win on numbers. Numbers will be the only thing that beats it. Numbers will win. The 3rd world is destined to inherit the Earth, and our low birth-rates mean that we're all fucked and going to spiral into extinction. There is no medicine to deal with the disease that beats our medicines. And there isn't gonna be--by definition. And that disease will, inevitably, exist.
>>59427501
Ebola will pop up in Europe airborne and resistant to all drugs in February 2016. According to some guy on 8ch claiming to work for the WHO anyway.
>>59437667
nuke china when?
>>59428989
Odds are there will be one-two demographics that are unaffected.
Just hope to god it only hits the Arabs.
>>59441962
eh. depends on how fast the bacterias spread. if its too fast they wont outbreed shit
>>59442086
It's a highly mutagenic virus. Your friend might be wrong. It could totally be something else. But it's essentially a bad flu. And one of them will hit. It's a game of blackjack that such a flu hasn't hit us since the 1920s. But it's coming, and if you don't die from it? Your children definitely will.
>>59427501
>Americans
>Taking meds for no reason whatsoever
>Not building resistance before everyone else
LOL
>>59441896
Oh fuck off with your elitist shit.
I'm not OP but I am a medical technologist specializing in microbiology. I work at a major metropolitan hospital and I'm currently working on my PhD to become the head of a microbiology department. Prior to all of this, I worked as an environmental microbiologist for a government lab.
You don't have to be a fucking genius to understand the basic principles of microbial resistance and why this is such an important topic. Also, literally nobody in the scientific field is this fucking picky about who is and who isn't a microbiologist.
>>59429976
You must be one of those kids that needed a tard wrangler following you around.
>>59430278
http://phenomena.nationalgeographic.com/2015/11/21/mcr-gene-colistin/
>>59441896
>>Microbiologists are trained physicians
no they aren't
> would say. PhD can be completed within 1-2 years, biology degree takes 2-3 years.
I see why Greece is such a shithole now
>>59427501
Human gene editing will become massively funded after bacteria and viruses evolve too much to be medically treated.
>>59442357
>about who is and who isn't a microbiologist.
You're standing on the shores of lake Wobegon, friend.
>>59442311
>greece
>not paying debts
I LOVE YOU YERSINIA CHAN
>>59442439
Human gene editing is performed with viruses and bacteria. You misunderstand how impossibly-hard it is to accomplish.
>>59441896
Kek. I bet you call physicians doctors too, you fucking faggot.
>>59442439
>if we throw money at it, it will cure it!
t. cancer and AIDs researchers
>>59432411
Actually according to the docs and biologists I talk to its India who will most likely be ground 0 for a super bug. You wouldn't believe how many of them got a massive hate boner from hell for Indian medical practices.
>>59427501
For once OP is not a faggot.
The fact that rubbing your wounds with powdered sulfur and rock salt is now about as effective as going to a hospital should have people "mildly worried."
Even worse, the reduction in antiviral/antibacterial effectiveness is even worse for the world than OP or anyone else will see; because it affects our food supply, especially avian and mammalian species (not fish, mostly) which are routinely given all manner of pills, injections, and vaccinations none of which are surefire like they were a few decades ago.
Worse still, the increasing world population density means that every urban center on earth is now a ticking time bomb of bacterial resistance waiting to spawn, by dumb, random chance alone, the next spanish flu, or the next black death; we're even overdue now for a major catastrophic disease to hit based on the most mundane and expected mutation rates.
Imagine pneumonic plague 2.0 or super-ebola or something like that; it will inevitably happen, and with the world density so high and most of the world still living in the 1800s at best sanitation-wise, and with world travel a matter of mere hours, instead of days or weeks, the inevitable next plague will spread so quickly it will utterly overwhelm the world within a month and kill its way through people so quickly that the survivors, often weakened and sickly from secondary illness, will sit back with their mouths gaping in horror- that includes even the most sadistic nihilist.
>>59427501
>Expect most of Africa, India, South America, Russia, and China to be gone by 2050
I might masturbate to this post tonight
>>59431018
it even SOUNDS cool.
>>59428711
>right on the cusp of nanomechanical immunity
<cough> bullshit <cough>
>>59441896
>>59427565
>>59427501
>>59428024
Not OP but I have a PharmD (Doctorate of Pharmacology) with a board certification in infectious diseases. I don't study the infections per se, but rather how to treat them.
And OP is right. We've only developed ONE new b antibiotic class in the last twenty years (fifth gen ceph, and even that is just an extension of what we have). Antibiotic resistance will occur in our lifetime, bet on that.
The world will eventually run out of fresh water
The world will eventually run out of oil
The world will eventually become unstustainably populated at this rate
But not in our lifetimes. Not in the next 100 years.
Untreatable sinus infections that progress into resistant pneumonia is already here, and WILL be here before too long.
There already does exists AIRBORNE infections that are TDR (totally drug resistant) in poo-land.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631557/
''Last but not the least; as far as, there is no cure for TDR-TB patient, hence it is not exaggeration to say that world is on danger of untreatable drug resistant tuberculosis strain. Therefore, if authorized health organization do not consider immediate action plan for such bacilli, then we may face a new outbreaks of untreatable TB.''
I now open the floor for questions.
>>59442621
>and most of the world still living in the 1800s at best sanitation-wise,
especially with them all flooding first world nations
fuckers don't even wipe their hands as they sneeze into them and think its totally normal
>>59442621
>especially avian and mammalian species (not fish, mostly) which are routinely given all manner of pills, injections, and vaccinations none of which are surefire like they were a few decades ago.
Actually? That's less of a problem than you think. You're talking about a four-year hit to a market. We have such absurdly-large control populations that, when the problems occur? We just kill the whole, vulnerable population, and let it go. Mad-Cow made these principles into policy. We're all-good on the defense against the livestock strains. It'll hit--but that's not where it'll come from.
>>59442621
>Imagine pneumonic plague 2.0 or super-ebola or something like that; it will inevitably happen, and with the world density so high and most of the world still living in the 1800s at best sanitation-wise, and with world travel a matter of mere hours, instead of days or weeks, the inevitable next plague will spread so quickly it will utterly overwhelm the world within a month and kill its way through people so quickly that the survivors, often weakened and sickly from secondary illness, will sit back with their mouths gaping in horror- that includes even the most sadistic nihilist.
I'm so fucking hard
>>59442743
>Untreatable sinus infections that progress into resistant pneumonia is already here, and WILL be here before too long.
>
>There already does exists AIRBORNE infections that are TDR (totally drug resistant) in poo-land.
this is all I was trying to convey
everyone is so worked up about shit that will effect us down the line that they're not noticing the massive problem right infront of us
this isn't something that will effect us eventually
it's already in progress
>>59442783
My point being that the damage will linger long after any primary wave of catastrophe hits- it doesn't even need to be a virus or bacteria, a supervolcano, asteroid, or massive quake would do much the same- with the economy and infrastructure fucked up all those extra viruses and bacteria that people no longer have substantial resistance to because of proper sanitation where it exists and proper medical infrastructure as well will come charging back in.
In any cataclysm in the new era more people will die of chronic diarrhea than the primary disaster; Haiti? check. Nepal? check. Hell people got cholera after Katrina hit too.
>>59427501
hi Leon
so if i can shit on my hands, what am i supposed to wash my hands with?
>>59442619
Tell me friend, does this link trigger you?
http://www.chinasmack.com/2010/pictures/filthy-india-photos-chinese-netizen-reactions.html
>>59442913
>all those extra viruses and bacteria that people no longer have substantial resistance to because of proper sanitation where it exists and proper medical infrastructure as well will come charging back in
Nope.
That's just wrong. That won't be the killer. I mean sure: it might kill you or me. But it won't kill People.
People got cholera after Katrina--America didn't.
>>59442987
>chinese reactions
they have zero room to make fun of india
india is the only thing stopping them from being poo in the loo country
>>59435207
Wash your guaca bowle after each use.
>>59442884
Only the poor transmission rates of prior outbreaks have kept this world from utterly fucking imploding; swine flu, H1N1, ebola, etc; they were all either very quickly contained or had a low transmission rate that only became high due to cultural practices- eating those cat-monkey-whatever things in China, handling corpses without protection and bathing them in west Africa, and so forth.
But it's only a matter of time before a disease of some sort evolves in this manner and either has a high enough transmission rate to "go viral" (pardon the pun) or manages to attain critical mass due to the cultural practices or density of whatever primary zone it happens to arise in.
>>59442743
Is there a solution to this "resistance crisis"?
Is this entire thread fearmongering, or are the things people saying reasonable? (As in, Reasonably scary?)
How fucked is North America?
>>59442888
checked trips.
I got yo back, OP. I've been telling people about this tsunami coming for years, ever since I started studying for my board certification, and have ICU physicians telling me what they USED to give for these infections.
Shit is getting really bad, and no one fucking knows.
We dont' develop anymore. Pfizer just shut down their abx branch completely. No money to be made. We're gonna get butt-fucked. Hard.
I started my job here at my hospital in Jan, and I've seen two cases of VRE, and one CRE.
CRE, for you lay-fags, is carbapenum resistant enterococcus. Carbapenums are the strongest antibiotics we have. Our nuclear bombs. If an infection survives this, we have nothing else to throw at it unless we go way back with WWII era shit like chloramphenicol (which wrecks your liver, kidneys, hearing, sight, and causes 'grey baby syndrome').
>>59436268
false
anti-bacterial soap uses alcohol, it has nothing to do with antimicrobial resistance
alcohol is like detonating a nuke on bacteria
>>59443041
That's because the disaster was localized.
Extrapolate that to a disaster affecting multiple nations at a severe enough level and bye bye resistance; your population will be hungrier, colder, sometimes homeless or living in tents, with a crippled medical system and limited access to clean water.
Perfect conditions for a mass die off of a good 10 to 25 percent of your population above whatever was dead from the primary disaster.
>>59431304
FUCK OFF RABBITPOSTER
>>59428989
Is this a welfare and autism convention?
>>59443126
Just be sure to buy some land in Wyoming.
>>59443190
that's from an actual bernie sanders rally
notice the guy in front is wearing a bernie sanders pin
>>59427501
>>59442621
Don't worry, the free market will fix it.
>>59443126
We have some hope in the form of genetics-based medical breakthroughs it's a matter of whether the technology advances far enough to account for the slow, ignominious death of chemical based treatments.
There's also hope in herbalism and the whole probiotic thing; one thing that does consistently fuck up the "bad" bacteria is an absence of free space to populate. Maybe they'll start smearing operation rooms in yogurt paste or something.
Wow, there are some people who are trying SUPER hard to give the impression that op doesn't know what he's talking about.
Op is right, do some Googling, twats
>>59431500
>investing in nanotechnology will be profitable then
https://www.youtube.com/watch?v=RhMsboqMMzs
>Expect most of Africa, India, South America, Russia, and China to be gone by 2050
Sounds good to me
>>59443256
Hard to do when the pharmacological industry, the medical infrastructure, and the means of distributing services are all either nationalized or centrally administered through rampant and costly regulations.
Salk or Pasteur probably would be in prison if they existed today.
>>59443278
I'm not sure if it's normal or if I really hit a nerve in someone who wants to discredit my opinion
>>59443251
The resolution is too small, I guess their welfare phones don't have good cameras.
>>59443126
Honestly? Not that I can think of. It'd have to be some new class of super drug, but you have to understand that bacteria evolve VERY FAST. Some staph species have generation times of 30 minutes. Also, resistance genes can be transferred HORIZONTALLY within a bacterial colony (meaning, an inherent, genetic resistance to an antibiotic can be given to another adult cell, not just offspring). This is some next level shit.
I think that a 'probiotic' solution is the most practical. Bacteria compete within the body. Both within bacterial colonies, and with fungal. By dousing yourself with lame staph and strep, the 'good bacteria' could potentially fight off opportunistic infections.
http://www.upi.com/Odd_News/2015/09/12/Man-skips-shower-for-12-years-uses-bacterial-spray-to-keep-clean/4981442062916/
Similar to what this guy is doing.
>>59443322
Triple dubs never lie.
>all this talk about a bacterial apocalypse
>>59443272
>one thing that does consistently fuck up the "bad" bacteria is an absence of free space to populate. Maybe they'll start smearing operation rooms in yogurt paste or something.
This is correct. I theorize this will be the direction we go. See the link I posted in
>>59443411
>>59430461
So bacteria sex with a fancy name.
Good to know race mixing will be both the end and salvation of us all.
>>59441488
Canada-bro you're calling them antimicrobial diseases and that's not even a thing
>>59427501
Does this mean strep throat will kill?
>>59443513
I eagerly await our future as mossy, mushroom covered golems.
>>59427501
I nearly got fucked by MRSA a while ago. Took all the meds I was prescribed on the schedule I was told to take them on and I was fine for a while but it came back about a year later and I had to be put on another antibiotic. They had a pretty hard time actually finding something that would work. Apparently the second time worked and now I've been infection free for 3 years but I'd say we're gonna be fucked in a good 20 years give or take. Prey you all won the genetic lottery and have fucking incredible immune systems.
>>59443251
Also the multitude of Bernie Sanders signs in the background is a pretty solid clue
>>59429976
This is by far the stupidest thing I've read in this thread thus far. I'd like to pause a moment and reflect on just how stupid this is.
As if all of the bacteria on the planet are going to stop what they're doing, line up at Ausfag's CRISPR modification center, and patiently await changes to make them more vulnerable, THEN go back out into the world.
As if the bacteria which haven't been modified to keel over and die won't, oh, easily outreproduce THE DEAD ONES BECAUSE THE FUCKING DEAD BACTERIA DON'T REPRODUCE YOU MORON.
Look, dude, I want you to find some sources of radition, like a thousand smoke detectors, and I want you to hold them up against your nuts until you are sterilized.
>>59443599
https://en.wikipedia.org/wiki/Scarlet_fever
>>59442621
>rubbing your wounds with powdered sulfur and rock salt is now about as effective as going to a hospital should have people "mildly worried."
Does this actually work? Would it be a good idea to just use this method of treatment instead of going to the hospital?
>>59443411
>Also, resistance genes can be transferred HORIZONTALLY within a bacterial colony (meaning, an inherent, genetic resistance to an antibiotic can be given to another adult cell, not just offspring).
Okay, now this is getting spooky.
>>59443599
yeah, pretty much. Eventually will traverse down into the lungs and cause pneumonia, still be resistant, and you'll die.
>>59443411
Not going to lie, pretty spooked right now.
Aside from the AO spray, what else is there that can be done to survive this?
>>59443599
They'll start calling it Scarlet Fever again and everyone will be terrified of it.
>>59443308
>Japan and Australia will likely have a very high chance of being completely unharmed.
This also sounds good to me
>>59431420
Because big pharma makes Lockheed Martin and BP look like fucking saints in comparison
>>59443712
In the near future I speculate that excoriating wounds, treating them with bacterial probiotics, or administering herbal compounds will make a substantial comeback.
They might as well bring back old school serum treatments too since they're probably about as useful as vaccines and antibiotics these days.
Obviously I wouldn't advise you not to seek medical treatment for anything you judge to be potentially life threatening, but, why go to the hospital for a minor cut or bruise and risk untreatable staph resulting in literal amputation?
>>59440199
Antibiotics are very scattershot in their approach.
Women get yeast infections, often, from taking antibiotics because the "good bacteria" get killed off. Similarly, a lot of people get diarrhea the same way, hence people taking probiotics with their medications to replentish the typical gut bacteria.
>>59443823
>>59443772
horizontal transfer isn't all that new, we've known about it for awhile. It's only significant because of it's ability to move a resistance gene within the same generation.
But yeah, it's pretty spooby
As of now, all we've done is fiddle with antibiotic amts, just absolutely loading people up with them, side effects be damned.
>>59443916
Ah I see, thanks for the information, very useful to know.
>>59427501
Why are these "microbes" just appearing now?
>>59441531
Not completely true, but kinda. They kill indiscriminately among the class they're designed to kill. (gram + , gram -, atypical, etc...)
>>59444013
Alright, cool, but can anything be done?
>>59444086
To increase chances of survivability that is
>>59441896
>>59427501
>>59428174
Scientist here. not going to say where I now work but I've worked for the US gov't at the NIH's NCATS, NCI, and have been shortlisted at NASA.
I just got a first author JCI
I met with the VP of a huge company about the need for an ebola vaccine a year before the outbreak. I was told it simply wasn't profitable enough to pursue as it was an orphan disease at the time.
These people are completely wrong. Congrats on being incredibly short-sighted OP. But so goes with a PhD student that seeks novelty in minutiae. (you got drunk off your lab's kool-aid.)
Here's why superbugs arent going to threaten humanity.
1) new drugs aren't made because they are simply not profitable. Once incentivized, it would be a very very short time before they were made. (think back to how quickly an ebola vaccine was made in reaction to the outbreak.)
2. Drugs for the DR strains already exist but are not for public use.
3. You don't know what you don't know. Meaning you have no idea what is yet to be discovered. EVEN IF there were no drugs that can be used, it is likely that new drugs will be found.
4. You guys have no knowledge of immunotherapies of disease ie anthrax.
Look up Serguei Popov, a defector of the soviet union to the US.
tl;dr
this is babby's first kool-aid shill for his own work. The world is a lot bigger than some lab at Upenn buddy
humans lived without anti-biotics for hundreds of thousands of years until just the last century
it's gonna get shitty but we'll muddle through like we always have, civilization isn't going to collapse, we just have to be more careful we don't catch diseases and the mortality rate of infants and old people is going to rise and it might be a bit harder to raise livestock but it doesn't seem to me like we're gonna get wiped
might even do the world some good if a billion or two third worlders bite the dust
>>59444086
yeah, the same way cancer can be cured.
I suspect it CAN be done, but it hasn't yet, and whoever does will be like our memelord Brian Henderson
>>59444141
I have a feeling that a bunch of us will be biting the dust too is this comes crashing down in full swing
No body would be safe in the era of globalization, where people can travel across the world in mere hours
>>59444224
>like cancer
Great.
>>59444140
Also humans are in equilibrium with disease, if we take a population's perspective.
People have commensal bacteria on them that can easily necrotize. Look up fournier's gangrene.
People get TB and it becomes latent and doesn't fuck with them given their immune systems.
Certain people with certain genetics are predisposed to illnesses and infections. Ever heard of cystic fibrosis and why people walk around with the mutation?
There's a lot of ignorance here on /pol/ but just because you're a phd student doesn't mean you have the authority or knowledge to get on a pulpit and try to disseminate fear because you lack perspective and knowledge. A little bit of knowledge is dangerous in this case.
>>59430791
>stop washing your hands and using soap
You're an idiot.
>>59444140
Don't push the fear, fear is good.
>>59444239
This will be a major political talking point. Communicable diseases coming across the border. Measles ALREADY IS making a comeback due to spics.
>>59444288
yeah, exactly, and I mean it in the same way. Except we're actually making a lot of progress on cancer (look up PD-1 and PD-L1 blockers, new genetic testing, etc...) Antibiotic research hasn't moved fuckign at all except one fifth generation cephalosporin and Fidaxomycin, which only treats one disease caused by one bacteria.
Better start building Vault 101 now, lone wanderer.
>>59444063
Not OP, but we're literally forcing them to evolve by killing large numbers of them and leaving increasingly resistant survivors.
Most people don't follow the full antibiotic course when sick- they take the pills until they feel better then, like a dumbass, they stop; but this means even if they feel fine they can spread the last few, more rugged survivors that would have been dead had they taken the last few pills and not been an impatient fuck.
Administering antibiotics to animals is even worse; factory farms aren't sanitary anyways and the people there aren't necessarily medical experts; they cut corners if they can, and their reasoning almost surely, in many cases, is "yeah old bessie is healthy as a horse... cow... no need for that recommended third injection, I'll save the extra twenty and go get a couple six packs instead."
>>59444367
It's getting worse an dworse though.
>>59444239
we'll probably be old by then and ready to die anyway
>>59444503
Eh, I think it'll be a problem in our lifetimes, anon. AIDS is only 30 years old, btw.
>>59444367
So has this thread been a series of fearmongering then?
>>59444140
Well you certainly never studied biology or ecology because you appear ignorant of the bottleneck effect and its interplay with selective forces.
We're bottlenecking bacterial and viral species on a regular basis on a micromanaged level using the population as a sort of self contained laboratory by handing out antibiotics like candy and not making sure people take them long enough to truly get rid of the last bacterium.
Your claim regarding profit incentive is half true; but when we inevitably see the next real, honest to goodness spanish flu/plague 2.0, it is likely to spread far faster than even heavily incentivized treatments can be developed.
New drugs can be found, but trying to find them as your population begins freefalling because of that one lonely random mutation in some godforsaken corner of the Amazon or the Euphrates valley or Tibetan steppe has unleashed a disease that transmits readily and kills easily is going to be a pretty difficult endeavor.
>>59427501
>>59428174
Ahh yersinia.
there was a paper about PLA that came out from northwestern. I forget the name of the lab.
basically OP, I read it and knew of the data before it was published.
You really are wrong. but at least you are proud of your work.
>>59444694
yes.
>>59444774
rad. good thing I scroll straight to the bottom
>>59444753
buddy you have no idea. studying "biology" and "ecology" is like studying philosophy .
you are literally talking in buzzwords
you also have no idea of what you are talking about
>>59444367
>Attempts to conflate one disease with the probability over time of even a completely random and remote mutant strain becoming the next plague.
What are you smoking, Britisher?
>>59431896
Don't forget the proud Prussian military heritage.
https://www.youtube.com/watch?v=U3Kdic-Z2-4
>>59444833
>I going to listen to what a single person says in a thread with hundreds of posters
>>59444883
I'm not even british.
>>59444883
if you were analytical you would be able to tell I use american spelling, and that I said I worked for the US govt
>>59444774
What about all the other people posting otherwise?
I mean, something surely is convincing large numbers of people that the next plague will happen within the next few decades...
>>59444877
Yes, clearly biological science has nothing to do with biological life forms... like bacteria...
Did you study at a creationist "college"? I have to assume so since you apparently forgot to study natural selection; resistant disease has arisen because of piss poor management regarding treatments that never should have been left to people to self administer. Now we have cases where someone gets staph, can't really be treated, and where they're basically told "hope for the best because if it gets worse you're losing that leg right up to the knee."
The concept that modern medical infrastructure is so advanced that an epidemic of plague-like proportions is no longer possible is absolute and complete stupidity; the density of the world and lack of progress sanitizing the third world virtually ensures that any progress made in the civilized world is offset by setbacks elsewhere; for years they cried with joy about how polio would be the next smallpox and soon be in the dustbin of history, and now it's resurging not because of a natural disaster or a mutation, but because of fanatic militants alone; the instability of the third world has effectively prevented us from wiping out a whole host of diseases that shouldn't even exist anymore.
Queue the victorian disease (tuberculosis, since you probably don't have a grasp of history any more than you do biology or evolutionary theory in general) and its own resurgence. Any destabilization in richer areas where it is being suppressed by the absence of malnutrition and exposure to the elements and you have yet another pandemic to deal with.
In time, it is not likely but rather a certainty.
>>59445077
You work for the US government?
So does the white house janitorial staff.
So does Rick Santorum. Let's ask him about evolution and the germ theory.
>>59444141
They also didn't live in cities of 20 million people with transport across the world in days.
>>59445176
the way to tell the difference between a scientist and a writer is that the scientist gets to the point.
but I'll tip my fedora toward your attempt at saying I went to a "creationist college."
>>59445149
do you really think listening to the consensus is the best option here?
>>59445399
Dont get me wrong, I want to believe you
But when I googled this, coupled with reading the other statements being presented here, it sounds like this 'plague' is actually going to happen
So you're for sure, though right?
>>59445278
You can claim whatever you want here; but I can guarantee you're not a "scientist" unless that's your way of saying you played around in your high school chemistry lab and thought it was fun to react things together with your basic, rudimentary knowledge of chemical processes.
No scientist is ignorant of the most basic tenets of evolutionary theory, nor would any actual scientist ever make the astonishing and retarded claim that the medical infrastructure is capable of dealing with a pandemic which is a certainty, not a probability, based on all of observed human history.
No, scientists do not make such a mistake, only ignorant laypeople do; science recognizes the inevitability in time of such things because it realizes that the way we view Victorian science will be the way scientists a century from this day view science today, as primitive, and they will casually joke about "how did they fucking survive?"
I speculate that you're a nurse, or perhaps an intern or something, and nothing more.
>>59445399
The scientific consensus happens to agree with the general consensus of this thread; the scientific establishment is well aware of the threat of untreatable illness and the resurgence of exotic disease.
Your shitposting to the contrary is meaningless; your christian "college" degree in exorcism-based disease treatment means nothing to me.
