Lupin III
Cowboy Bebop
Outlaw Star
Trigun
Hellsing
Ghost in the Shell
Space Dandy
Eureka Seven; Holland
Wolf's Rain; Tsume
JoJo part 3; Joseph and Avdol
JoJo part 4; Jotaro
JoJo part 5; Jotaro
>>95117
Gintama
Gungrave
Darker than Black
The Legend of the Legendary Heroes
Monster
Speed Grapher
Shigurui
Black Jack
Welcome to the NHK
Nodame Cantabile
Usagi Drop
Sayonara Zetsubou Sensei
Wolf and Spice
Mushishi
Black Lagoon
Nana
Macross Plus
Space Brothers
Toriko
Cooking Papa
Kaiji
City Hunter
Rurouni Kenshin
Arakawa under the Bridge
Jesus, I could go on and on.
Berserk
Samurai Champloo
Fist of the North Star
Dead Leaves
Bubblegum Crisis (i think?)
JoJo, up until Diamond is Unbreakable
Strait Jacket
Perfect Blue
Blue Gender
Welcome to the NHK
Steins;Gate
There's a literal truckload. The "anime is all highschool" meme is just a meme.
Macross plus
Rakugo
Joker game
Mobile Suit Gundam CCA
Dai-Guard
I'm pretty sure the guy from Aoi Bungaku is over 20, but he's around college aged from what I remember.
Rage of Bahamut
Osomatsu-san
Dimension W
Gate
Death Parade
Ninja Slayer
Shirobako
Turning Girls
Sayonara Zetsubou Sensei
One Outs
Paprika
Patlabor
Golgo 13
>>95135
>Golgo 13
How the fuck did I forget about that. I'm embarrassed...
>>95141
Great Teacher Onizuka
Barakamon
Ninja scroll
Genshiken
Afro Samurai
Planetes
Akira
Bartender
Detroit Metal City
Kuuchu Buranko
II Can't Understand What My Husband Is Saying
One Outs
Basilisk
Tokyo Godfathers
Space Dandy
The Animatrix
Halo Legends
Devil Maycry
The FIve Star Stories
The Laughing Salesman
Otaku No Video
Since this partly relates to my interests I'll do one but specificall for women:
Main Character:
Paprika
Perfect Blue
Millennium Actress
Ghost in the Shell
Kanashimi no Belladonna
Cutie Honey
Omoide Poporo
Bubblegum Crisis
Kuragehime
Wolf Children
Shinsekai Yori (after time skip)
Woman Called Fujiko Mine
Shirobako
Iria
Seirei no Moribito
Birdy the Mighty
Kara no Kyoukai
Jormungand
Mardock Scramble
Appleseed
Dirty Pair
Noir
In duo with male protagonist:
Black Lagoon
Katanagatari
xxxHolic
East of Eden
Hellsing Ultimate
Redline
Spice and Wolf
Arakawa
Kemonozume
Death Parade
Planetes
Part of larger main cast:
Casshern Sins
Cowboy Bebop
Ergo Proxy
Patlabor
Uchuu Senkan Yamato 2199
Baccano
Giant Robo
Genshiken
Trava
Lodoss
Durarara
Important love interest:
Berserk
NHK
Garden of Words
Macross Plus
Ruroni Kenshin
>>95223
>durarara
Isn't like a good half of the main cast under 20?
>>95240
Celty is above 20 for sure and so is that blonde chick from the new seasons. Honestly I kind of forgot about that since I don't really care much for the kid characters. But I guess I should have emphasized that.
So just to be clear, shows that are somewhat exceptions:
Wolf Children - main character is a mother, but her children are also part of the cast
Birdy - adult female characters shares a body with a teenage boy
Jormungand - The two main characters are the adult female and a child soldier
xxxHolic - main teenage boy character works for an adult woman
Giant Robo - Larger cast, most of them are adults besides main char who is a boy
Garden of Words - Teenage boy falls in love with an adult woman.
The only ones that I could think of that weren't mentioned in this thread are:
Honey and Clover
One Punch Man
Tatami Galaxy
Panty & Stocking
Kaiji
The Big O
Vampire Hunter D
Just gonna post some ones that weren't already posted:
Battle Programmer Shirase
Gangsta
Gugure! Kokkuri-san
Gunbster (maybe)
Hataraku! Maou-sama
Hen Zemi
Inuyasha (technically)
Jin-Roh
Junketsu no Maria
Legend of the Galactic Heroes (both protags start young but story follows them for years)
Log Horizon
Noragami
Oji-san to Marshmallow
Overlord
Panty & Stocking
Porco Rosso
Psycho Pass
Rail Wars
Scryed
Sekkou Boys
Servant x Service
Subete ga F ni Naru
Tiger and Bunny
Utawarerumono (+Itsuwari no Kamen)
Witch Hunter Robin
Young Black Jack
This isn't really a challenge, OP. You should have asked for protagonists that are over 40.
>>95301
>Gunbster
Noriko is 16, though I also had to check while typing out titles.
There's a lack of oldies:
Grendizer
Golden Boy
Space Pirate Captain Harlock
Maison Ikkoku
The Rose of Versailles
Gunnm
Captain Future
Sherlock Hound
Ulysses 31
Cat's Eye
Space Cobra
Ah My Goddess
Les Misérables
You're under arrest
New Cutie Honey
Bastard
Berserk
Vampire Hunter D
Hokuto no Ken
Devilman
Appleseed
3x3 eyes
The Transformers
Kinnikuman
The Swiss Family Robinson
Nobody's Boy Remi
Galaxy Express 999
>3 mentions of Macross Plus
>None for 7
Basara's 22 even though he doesn't act it.
>>95319
But then again, it's not like Isamu or Guld are the pinnacle of maturity themselves~
>>95314
Other protagonists are older though. Plus there's the whole relativity thing.